Resident Evil: Degeneration, known as in Japan, is a 2008 Japanese adult animated biopunk action horror film directed by Makoto Kamiya. It is the first full-length motion capture animation feature in Capcom's Resident Evil franchise. The film was made by Capcom in cooperation with Sony Pictures Entertainment Japan. Degeneration made its premiere at the 2008 Tokyo Game Show and was released theatrically on October 17, 2008.

Plot

In November 2005, Harvardville Airport falls victim to a T-virus attack both from inside the terminal and a crashlanded airline plane. TerraSave worker Claire Redfield coincidentally runs into Senator Ron Davis, a vocal opponent of TerraSave, and they are forced to hide in the VIP lounge with Rani, niece of a TerraSave employee. By nightfall, the airport has been locked down by the local Special Response Team and the United States Army, aiding evacuated survivors. Officers Angela Miller and Greg Glenn are joined by federal agent Leon S. Kennedy. Claire's group is rescued; however, they are forced to leave the infected Greg. Trucks from pharmaceutical corporation WilPharma arrive to administer a T-virus vaccine they created, but are destroyed by explosives. Leon reveals that a terrorist has threatened to unleash the T-virus throughout the U.S. should government officials involved in its creation not be revealed by midnight.