Route 666 is a 2001 action horror film directed by William Wesley and starring Lou Diamond Phillips, Lori Petty, Steven Williams, L.Q. Jones, Dale Midkiff, Alex McArthur, and Mercedes Colon. In the film, government agents are besieged by the ghosts of a massacred chain gang while driving down a desert highway.

Plot

Sitting alone at a roadside bar in Arizona, Fred "Rabbit" Smith drinks nervously. Two people named Jack La Roca and Stephanie enter the bar. Rabbit uses the restroom, followed by Jack, who handcuffs him. He reveals that he and Steph are Federal Marshals assigned to capture Rabbit and bring him to court in Los Angeles to testify against his former boss, a mobster named Benny "The Buzzsaw" Buffalino, who has recently become partners with the Russian Mafia. Benny contracts Russian hitmen led by Sergei to hit Rabbit before he can testify against them. He was initially going to testify in exchange for complete immunity but ran after the Russians came to kill him. They are hunting him, too. Jack calls for a Suburban driven by four other marshals to pick them up before Sergei and his crew of killers arrive with heavy firepower. They leave out the back and battle the assassins until marshals; Nick, Mary, P.T., and Joe arrive between them. They manage to kill all assassins but Sergei. Jack and Rabbit use Rabbit's car to escape the same path as the other marshals (including Steph in the truck). Jack manages to shoot Sergei's tires out before leaving.