Dr. Pyckle and Mr. Pryde (also Dr. Pyckle and Mr. Pride) is a 1925 American silent, black-and-white comedy film, directed by Scott Pembroke and Joe Rock (also the producer).

Plot

Dr. Stanislaus Pyckle, (a play of the actor's name, Stan Laurel), successfully separates the good and evil of man's nature with the use of a powerful drug -- "Dr. Pyckle's 58th Variety", a spoof of "Heinz's 57". Transforming into the personality of Mr. Pryde (again Laurel), he terrorizes the town with unspeakable acts including stealing a boy's ice cream, cheating at marbles, and popping a bag behind a lady pedestrian. The townspeople track him down where Mr. Pride locks himself in the laboratory and transforms back as Dr. Pyckle. The doctor assures the townspeople that he hasn't seen the "fiend" they were after. While he talks, the drug used for the transformation spills in the plate of food of the doctor's dog. Dr. Pyckle confronts the fiendish dog when he locks the door and the townspeople leave. But once again, Mr. Pride emerges and brings havoc to the town, and again is chased down by the townspeople. He enters the lab and transforms back into Pyckle, and again assures the townspeople he has not seen the fiend. His assistant (Julie Leonard) begs the doctor to open and comfort him, but he transforms back into Mr. Pride. He opens the door to the assistant and locks it again. She screams seeing Pride and the townspeople hurry back, before the assistant can knock Pride down.