Despicable Me 4 is a 2024 American animated comedy film produced by Universal Pictures and Illumination, and distributed by Universal. It is the sequel to Despicable Me 3 (2017), the fourth main installment, and the sixth overall installment in the Despicable Me franchise. The film was directed by Chris Renaud, co-directed by Patrick Delage (in his feature directorial debut), produced by Chris Meledandri and Brett Hoffman, and written by Mike White and Ken Daurio. It stars the voices of Steve Carell, Kristen Wiig, Pierre Coffin, Joey King, Miranda Cosgrove, Steve Coogan, Sofía Vergara, Stephen Colbert, Renaud, Madison Polan, Dana Gaier, Chloe Fineman, and Will Ferrell. The film sees reformed supervillain and secret agent Gru (Carell) relocate his family to a safe house when his old rival Maxime Le Mal (Ferrell) seeks revenge. Subplots deal with Gru's family adjusting to their new lives, teenage neighbor Poppy Prescott (King) trying to follow in Gru's villainous footsteps, and a group of Gru's Minions (Coffin) becoming superheroes.

Plot

Anti-Villain League (AVL) agent Gru attends a reunion at his alma mater, Lycée Pas Bon. There, he reunites with his school rival Maxime Le Mal, who harbors a grudge towards Gru for stealing his talent show act, singing "Karma Chameleon", when they were in school. Maxime reveals he has enhanced himself into a cockroach hybrid, making himself superpowered, and plans to conquer the world, but Gru and the AVL arrest him. Maxime escapes from the AVL prison the next day with the help of his girlfriend Valentina. He develops a ray gun invention that turns people into human-roach hybrids, which he plans to specifically use on Gru's infant son Gru Jr, as revenge.