Sister, Sister is a 1987 American Southern Gothic psychological horror film directed and co-written by Bill Condon in his directorial debut, and starring Eric Stoltz, Jennifer Jason Leigh, and Judith Ivey. It follows two sisters operating an inn in the Louisiana bayou, whose dark secrets come to light after the arrival of a male guest.

Plot

Lucy Bonnard, a young woman with a history of mental illness, helps her older sister, Charlotte, operate the Willows, an inn at their familial plantation in the Louisiana bayou. The sexually-frustrated Lucy is unsuccessfully courted by Etienne LeViolette, her childhood friend who now works as a handyman for the sisters. Charlotte is carrying on a romance with town sheriff Cleve Bonnard, but he ends the relationship, blaming Charlotte's overbearing devotion to caring for Lucy.