Zerophilia is a 2005 romantic comedy film with speculative-fiction elements directed by Academy of Motion Pictures' Student Academy Award-winning director Martin Curland and produced by Microangelo Entertainment. It is about a young man who discovers that he has a genetic condition which will cause a change of sex following each orgasm. It was filmed in Fall Creek, Oregon.

Plot

After Luke (Taylor Handley) loses his virginity to a random stranger he meets on a camping trip (Kelly LeBrock), he soon finds parts of his body intermittently transforming into those of a female's body and back. Upon returning from his trip, Luke takes his car for repairs and meets the shop's owner Max (Kyle Schmid), whom Luke envies for exhibiting the kind of suave, confident masculinity that he himself cannot, and Max's sister Michelle (Rebecca Mozo), a recent transfer student at Luke's school whom Luke had been fostering a crush on. Luke asks Michelle out and the two hit it off, with Luke interested in Michelle's down-to-earth bluntness and Michelle in his sensitivity, but Michelle is somewhat wary of him due to having recently gotten out of a relationship with an ex-boyfriend who had cheated on her.