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Up in Smoke (also referred to as Cheech & Chong's Up in Smoke) is a 1978 American buddy stoner comedy film directed by Lou Adler in his directional debut and starring Cheech Marin, Tommy Chong, Tom Skerritt, Edie Adams, Strother Martin, and Stacy Keach. It is Cheech & Chong's film debut.

Plot

Anthony "Man" Stoner, an unemployed, marijuana-smoking drummer, is told to either get a job by sundown or be sent off to military school by his parents. Man leaves the house and later becomes stranded on the highway. Man is picked up while hitchhiking by the equally enthusiastic stoner Pedro de Pacas, and the two share a large joint, which is revealed to contain Labrador feces after the dog ate Man's supply. When Pedro freaks out and seems to have trouble breathing, Man accidentally gives him an extremely powerful dose of LSD. The police find their car parked on a traffic median with them in it, discover that they are high and arrest them. At trial, the pair are released on a technicality after Man discovers that the judge is drinking vodka.