Grand Canyon Massacre (Italian: Massacro al Grande Canyon, lit. "Massacre at Grand Canyon") is a 1964 Italian Spaghetti Western filmed in Croatia starring James Mitchum, Milla Sannoner, and George Ardisson. It was directed by Sergio Corbucci and produced by Albert Band. The film's theme song was performed by Rod Dana. The film has nothing to do with the Grand Canyon.

Plot

Wes Evans has completed his quest in finding and killing the Slade brothers, who have murdered his father, the sheriff of Arriba Mesa. Returning home, Wes is stopped by a large amount of gunmen in Butte Canyon, whose presence is a mystery. Wes escapes and returns home to Arriba Mesa. The judge offers him the job as sheriff and Cooley, the holder of the office and a friend of Wes, is anxious to step down. Wes however only wants to settle down, but when he learns that his love Nancy (who believed Wes to be dead) has married Tully Dancer, he decides to leave again.