Jungle Cruise is a 2021 American fantasy adventure film directed by Jaume Collet-Serra from a screenplay written by Glenn Ficarra, John Requa, and Michael Green. It is based on Walt Disney's eponymous theme park attraction. Produced by Walt Disney Pictures, the film stars Dwayne Johnson, Emily Blunt, Édgar Ramírez, Jack Whitehall, Jesse Plemons, and Paul Giamatti. It tells the alternate history of the captain of a small riverboat who takes a scientist and her brother through a jungle in search of the Tree of Life while competing against a German expedition, and cursed conquistadors.

Plot

In 1556, Don Aguirre leads Spanish conquistadors to South America to search for the Lágrimas de Cristal Tree, whose flowers cure illness, heal injuries, and lift curses. After many conquistadors die, the Puka Michuna tribe heals the sickened survivors with the Tree's flowers. When the tribal chief refuses to reveal the Tree's location, Aguirre stabs him and burns the village. The dying chief curses the conquistadors, making them immortal and unable to leave sight of the Amazon River without being dragged back by the jungle itself.