Anacondas: The Hunt for the Blood Orchid is a 2004 American action adventure horror film directed by Dwight H. Little. It is a stand-alone sequel to the film Anaconda (1997) and the second installment of the Anaconda film series. It stars Morris Chestnut, Matthew Marsden, KaDee Strickland, Eugene Byrd, Salli Richardson-Whitfield, Nicholas Gonzalez, Karl Yune and Johnny Messner. The film follows a team of researchers set for an expedition into the Southeast Asian tropical island of Borneo, to search for a sacred flower which they believe will bring humans to a longer and healthier life. They soon become stalked and hunted by the deadly giant anacondas inhabiting the island.

Plot

A team of researchers funded by New York pharmaceutical firm Wexel Hall, including Gordon Mitchell, Dr. Jack Byron, Sam Rogers, Gail Stern, Cole Burris, and Dr. Ben Douglas, leave for a jungle in Borneo to search for a flower called Perrinnia immortalis--"the Blood Orchid"—that they believe contains a fountain of youth, and the legendary Kukuusah Arkhurst which is believed to contain the "Lament Infinium" that will unlock all the knowledge of the universe; past, present and future. Jack convinces guide Captain Bill Johnson and his partner Tran Wu to take an unsafe path despite their misgivings. At one point, Gail falls into the water, loses her phone, and is attacked by a crocodile before Bill rescues her. Their boat goes over a waterfall and breaks apart. A giant anaconda emerges from the water and swallows Ben. The rest of the team reaches the shore. Bill assures them that it is the largest snake he has ever seen and that it should take weeks for it to grow hungry again. However, most of the team demands that the expedition be called off. They call Bill's friend, John Livingston, who lives on the river, to join them, but they find Livingston attacked and his boat wrecked.