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The Big Bus is a 1976 American satirical comedy film directed by James Frawley, and starring Joseph Bologna, Stockard Channing, and John Beck. Parodying the then-popular disaster genre, it follows the maiden cross-country trip of an enormous nuclear-powered bus named Cyclops.

Plot

Coyote Bus Lines' scientists and designers work feverishly to complete Cyclops, a state-of-the-art articulated jumbo bus, enabling man to achieve a new milestone in bus history, namely non-stop service between New York City and Denver. Almost immediately after the bus engine is equipped with nuclear fuel, a bomb goes off, critically injuring Professor Baxter, the scientist in charge of the project. Cyclops itself is undamaged, but Coyote Bus Lines has lost both its driver and co-driver.